Description

Fmoc-Val-Pro-OH CAS NO 109425-49-2 is a high-purity, protected dipeptide building block essential for solid-phase peptide synthesis (SPPS). Its core value lies in enabling the precise and efficient construction of complex peptide sequences for research and pharmaceutical development. This compound is critically needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, proteomics, and the development of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected dipeptide for the sequential assembly of peptide chains on resin.
• Pharmaceutical Intermediate: For the research and development of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Used in the synthesis of peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Combinatorial Chemistry Libraries: A fundamental building block for creating diverse peptide libraries for high-throughput screening.
• Academic & Industrial Research: Essential for biochemical studies, structure-activity relationship (SAR) analysis, and proteomics research.
• API Development: Serves as a critical intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs) for peptide-based drugs.

Basic Information

Product Name	Fmoc-Val-Pro-OH
CAS No.	109425-49-2
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	Fmoc-Val-Pro; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-L-proline; Fmoc-L-valyl-L-proline; Fmoc-Val-Pro-OH; N-α-Fmoc-L-valyl-L-proline; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanoyl-L-proline; Fmoc-Val-Pro; Fmoc-V-P-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Val-Pro-OH is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥98% (HPLC). Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation or storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	-40° to -50° (c=1, DMF)
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.