Description

Captopril n-Ethylmaleimide Sulfone is a specialized chemical derivative used primarily in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical profiling of complex active pharmaceutical ingredients (APIs). It is particularly valuable for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity building blocks for drug discovery, process development, and quality control applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and novel chemical entities.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, LC-MS, and other analytical techniques.
• Biochemical Research: Employed in proteomics and enzyme inhibition studies, particularly in research involving cysteine protease activity.
• Process Chemistry: Serves as a reagent or intermediate in the scale-up and optimization of API manufacturing processes.
• Academic Research: Utilized in university and institutional labs for chemical biology and medicinal chemistry projects.

Basic Information

Product Name	Captopril n-Ethylmaleimide Sulfone
CAS No.	109350-28-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline N-Ethylmaleimide Sulfone; Captopril NEM Sulfone; Captopril Maleimide Sulfone Adduct; 1-[2-Methyl-3-(sulfonyl)-1-oxopropyl]-L-proline N-Ethylmaleimide Derivative; ACE Inhibitor Maleimide Derivative; SQ 14225 NEM Sulfone
EINECS	Contact for details

Quality Control

Our Captopril n-Ethylmaleimide Sulfone is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure identity, purity, and consistency, with specifications aligned with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification, and impurity profiles is provided with every shipment to support your critical R&D and manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.