Description

2-(2,6-Difluorophenyl)Acetaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its core value lies in the reactive aldehyde group and the electron-withdrawing difluoro substitution on the phenyl ring, which directs subsequent reactions and influences the physicochemical properties of final compounds. This high-purity intermediate is primarily needed by pharmaceutical, agrochemical, and specialty chemical R&D and manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel small molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Fine Chemical Production: Integral in multi-step syntheses for flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	2-(2,6-Difluorophenyl)Acetaldehyde
CAS No.	109346-83-0
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2,6-Difluorophenylacetaldehyde; (2,6-Difluorophenyl)Acetaldehyde; 2-(2,6-Difluorophenyl)Ethanal; 1-(2,6-Difluorophenyl)-2-Oxoethane; α,2,6-Trifluorotoluene (misnomer, related); 2,6-DFPA; 109346-83-0; NSC 406915
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluorophenyl)Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress and oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.