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1,1'-Bis(1-Diphenylphosphino-1-Methylethyl)Ferrocene CAS NO 109313-83-9


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CAS No.:109313-83-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1'-Bis(1-Diphenylphosphino-1-Methylethyl)Ferrocene is a specialized, chiral ferrocene-based diphosphine ligand, a key component in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of optically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for developing new active ingredients and advanced materials.

Application

  • As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
  • Catalyst component in asymmetric C-C bond-forming reactions, including cross-coupling and allylic substitution.
  • Key reagent for the synthesis of enantiomerically pure pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
  • Use in the development of novel agrochemicals requiring specific stereochemistry for enhanced activity.
  • Research and development of advanced materials and specialty chemicals with chiral properties.
  • Catalyst screening and optimization in academic and industrial R&D laboratories.

Basic Information

Product Name 1,1'-Bis(1-Diphenylphosphino-1-Methylethyl)Ferrocene
CAS No. 109313-83-9
Molecular Formula C42H40FeP2
Molecular Weight 662.55 g/mol
Synonyms Josiphos SL-J009-1; (R)-(+)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; (R)-(+)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(tert-butyl)phosphine; (R)-(+)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(1,1-dimethylethyl)phosphine; 1,1'-Bis(1-diphenylphosphino-1-methylethyl)ferrocene; Josiphos-type ligand; Ferrocenyl diphosphine ligand
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Quality Control

Our production of 1,1'-Bis(1-Diphenylphosphino-1-Methylethyl)Ferrocene adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by NMR, HPLC, and elemental analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is easily oxidized and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Solubility Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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