Description

F Protein, Parainfluenza Virus 3 is a key viral surface glycoprotein essential for host cell membrane fusion and viral entry. This purified protein is a critical reagent for advancing research in virology, immunology, and vaccine development. It is primarily utilized by biotechnology and pharmaceutical companies, as well as academic research institutions, for applications ranging from assay development to immunogen production.

Application

• Vaccine Research & Development: Serves as a target antigen for immunogenicity studies and the development of novel vaccines against human parainfluenza virus type 3 (HPIV-3).
• Diagnostic Assay Development: Used as a coating antigen or standard in ELISA, lateral flow assays, and other immunoassays for the detection of HPIV-3 antibodies or antigens.
• Antiviral Drug Screening: Acts as a target protein in high-throughput screening platforms to identify and characterize potential fusion inhibitor compounds.
• Structural Biology Studies: Provides material for X-ray crystallography, cryo-electron microscopy, and other techniques to elucidate the fusion mechanism of HPIV-3.
• Immunology Research: Employed to study host immune responses, including neutralizing antibody characterization and T-cell epitope mapping.
• Cell Biology Research: Used to investigate the fundamental processes of virus-host cell membrane fusion and entry.

Basic Information

Product Name	F Protein, Parainfluenza Virus 3
CAS No.	109300-94-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HPIV-3 Fusion Glycoprotein; Parainfluenza Virus Type 3 F Protein; Fusion Protein (HPIV-3); HPIV3 F Protein; Paramyxovirus Fusion Protein (PIV3); Sendai virus-like fusion protein (related family); Human parainfluenza virus 3 fusion glycoprotein precursor
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized for identity, purity, and biological activity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific results for purity (e.g., by SDS-PAGE and HPLC), endotoxin levels, and functional activity are available upon request. Production follows quality management principles suitable for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C or below and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled, dry conditions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Consistent with expected molecular weight
Purity (SDS-PAGE)	> 90%
Purity (HPLC)	> 95%
Protein Content	≥ 1 mg/vial (Lot-specific)
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay (e.g., cell fusion inhibition)
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.