Description

4-(2,2,3,3-Tetrafluoropropoxy)-1-Nitrobenzene is a specialized fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing nitro group and the fluorinated alkoxy side chain, which imparts distinct electronic and physical properties to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where enhanced lipophilicity, metabolic stability, or specific receptor binding is required.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, especially in areas requiring fluorinated motifs for improved bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated structure can enhance activity and environmental persistence profiles.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Potential building block for electron-transport materials or fluorinated polymers used in OLEDs and other electronic devices.
• Advanced Polymer Modification: Incorporated into polymer backbones to alter surface energy, chemical resistance, and optical properties.
• Dye and Pigment Intermediate: Used in the synthesis of specialized nitro- and fluoro-containing dyes with unique color fastness and spectral properties.

Basic Information

Product Name	4-(2,2,3,3-Tetrafluoropropoxy)-1-Nitrobenzene
CAS No.	109230-72-0
Molecular Formula	C9H7F4NO3
Molecular Weight	253.15 g/mol
Synonyms	1-Nitro-4-(2,2,3,3-tetrafluoropropoxy)benzene; p-Nitrophenyl 2,2,3,3-tetrafluoropropyl ether; Benzene, 1-nitro-4-(2,2,3,3-tetrafluoropropoxy)-; 4-Nitrophenyl 2,2,3,3-tetrafluoropropyl ether; 2,2,3,3-Tetrafluoropropyl 4-nitrophenyl ether
EINECS	Contact for details

Quality Control

Our 4-(2,2,3,3-Tetrafluoropropoxy)-1-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results against agreed specifications. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The compound is stable under recommended storage conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.