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H-Asp-D-Pro-His-Asp-Phe-D-Trp-Val-D-Trp-Leu-Nle-Nh2 CAS NO 109212-72-8
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CAS No.:109212-72-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
H-Asp-D-Pro-His-Asp-Phe-D-Trp-Val-D-Trp-Leu-Nle-Nh2 is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound matters for its role in stimulating the secretion of growth hormone, making it a critical research tool in endocrinology and metabolic studies. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for growth disorders, metabolic conditions, and age-related muscle wasting.
Application
- Biomedical Research: Used as a reference standard and active agent in studies investigating the growth hormone axis, pituitary function, and hormone release mechanisms.
- Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of novel GHRH analogs for therapeutic applications.
- Endocrinology Studies: Essential for in vitro and in vivo experiments to understand the regulation of growth hormone secretion and its physiological effects.
- Metabolic Research: Applied in research models exploring the impact of growth hormone on metabolism, body composition, and tissue repair.
- Peptide Chemistry: Used as a building block or model compound in peptide synthesis and structure-activity relationship (SAR) studies.
- Veterinary Science: Investigated for potential applications in animal growth promotion and metabolic health.
Basic Information
| Item | Detail |
|---|---|
| Product Name | H-Asp-D-Pro-His-Asp-Phe-D-Trp-Val-D-Trp-Leu-Nle-Nh2 |
| CAS No. | 109212-72-8 |
| Molecular Formula | C73H94N18O16 |
| Molecular Weight | 1431.63 g/mol |
| Synonyms | GHRH (1-14) amide, human; Growth Hormone-Releasing Hormone (1-14) amide, human; hGHRH(1-14)-NH2; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 (fragment); GHRH analog; Growth hormone secretagogue peptide; Somatoliberin (1-14) amide; Contact for additional trade names. |
| EINECS | Contact for details |
Quality Control
Our H-Asp-D-Pro-His-Asp-Phe-D-Trp-Val-D-Trp-Leu-Nle-Nh2 is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For short-term use, store at 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (MS) | Consistent with theoretical molecular weight |
| Purity (HPLC) | ≥ 95.0% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
| Acetate Content (HPIC) | ≤ 10.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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