Description

Lorpiprazole CAS NO 108785-69-9 is a high-purity pharmaceutical intermediate and research chemical of significant interest in modern organic synthesis. Its primary value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly in the central nervous system (CNS) therapeutic area. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) exploration, and metabolic pathway research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling of related APIs.
• Process Chemistry: Integral to scaling up synthetic routes from milligram to kilogram scale during the drug development lifecycle.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in biological systems.

Basic Information

Product Name	Lorpiprazole
CAS No.	108785-69-9
Molecular Formula	C21H24FN3O
Molecular Weight	353.44 g/mol
Synonyms	Lorpiprazole; 1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-ol; DU-27716; FC-1157a; FC 1157a; Lorpiprazol; Lorpiprazolum; (RS)-1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-ol
EINECS	Contact for details

Quality Control

Our Lorpiprazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of specified impurities. A Certificate of Analysis (COA) detailing the results against agreed specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.