Description

Beractant is a complex, natural pulmonary surfactant derived from bovine lung extract, essential for maintaining alveolar stability and reducing surface tension in the lungs. Its primary commercial and medical value lies in its life-saving application as a replacement therapy for respiratory distress syndrome (RDS) in premature infants. This product is critical for pharmaceutical manufacturers developing and producing sterile injectable formulations for neonatal intensive care. Beractant CAS NO 108778-82-1 is supplied under stringent quality controls to meet the exacting standards of the global pharmaceutical industry.

Application

• Pharmaceutical Active Ingredient: The primary and most critical application is as the active pharmaceutical ingredient (API) in surfactant replacement therapies for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature neonates.
• Neonatal Critical Care Formulations: Used in the manufacture of sterile, endotoxin-free, ready-to-use suspension formulations for intratracheal administration in hospital and clinical settings.
• Biomedical Research: Serves as a vital research tool in pulmonary biology studies, investigating lung development, surfactant metabolism, and the pathophysiology of surfactant-deficient lung diseases.
• Drug Delivery Studies: Utilized in research exploring novel pulmonary drug delivery systems due to its biocompatibility and surface-active properties.
• Reference Standard: Acts as a biological reference standard in analytical laboratories for quality control and assay development of surfactant-based products.

Basic Information

Product Name	Beractant
CAS No.	108778-82-1
Molecular Formula	Complex natural extract; primarily phospholipids (e.g., Dipalmitoylphosphatidylcholine), neutral lipids, and surfactant-associated proteins (SP-B, SP-C).
Molecular Weight	Not applicable (heterogeneous biological mixture).
Synonyms	Beractant; Bovine Pulmonary Surfactant; Natural Lung Surfactant; Survanta (Brand Name); Calf Lung Surfactant Extract; CLSE; Pulmonary Surfactant, Bovine; Beraksurf; Surfactant TA; SF-RI 1.
EINECS	Contact for details

Quality Control

Our Beractant is manufactured and controlled under a strict quality management system designed for pharmaceutical-grade biological products. Each batch is subjected to a comprehensive battery of tests including, but not limited to, identification, phospholipid composition analysis, protein content, sterility, bacterial endotoxins, and biological activity testing. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) detailing all release specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store refrigerated at 2°C to 8°C. Do not freeze. Keep the container in the outer carton to protect from light. Handle under aseptic conditions appropriate for a sterile pharmaceutical product.

Specification

Item	Specification
Description	Sterile, white to off-white suspension
Identification (HPLC/Composition)	Complies
Phospholipid Content	Contact for details
Protein Content (SP-B & SP-C)	Contact for details
Biological Activity (Surface Tension)	Complies
pH	Contact for details
Sterility	Sterile (Compendial Test)
Bacterial Endotoxins	< Contact for details EU/mg
Particulate Matter	Compendial limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.