Description

Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic belonging to the β-lactam class. Its primary value lies in its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including many β-lactamase-producing strains. This makes it a critical active pharmaceutical ingredient (API) for manufacturers of oral antibiotic formulations targeting respiratory, urinary tract, and uncomplicated gonococcal infections. Global pharmaceutical companies and API suppliers require high-purity Cefixime CAS NO 108691-83-4 to ensure the efficacy and safety of finished drug products.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral solid dosage forms (tablets, capsules) and oral suspensions.
• Respiratory Infection Treatment: Formulated for treating bronchitis, pneumonia, and otitis media caused by susceptible organisms.
• Urinary Tract Infection (UTI) Treatment: Used in medications for uncomplicated UTIs.
• Sexually Transmitted Infection (STI) Treatment: A key component in single-dose therapies for uncomplicated gonorrhea.
• Veterinary Pharmaceuticals: Employed in antibiotic preparations for bacterial infections in animals.
• Research & Development: Serves as a reference standard and for the development of new antibiotic formulations or combination therapies.

Basic Information

Product Name	Cefixime
CAS No.	108691-83-4
Molecular Formula	C16H15N5O7S2
Molecular Weight	453.45 g/mol
Synonyms	(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(carboxymethoxyimino)acetamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefixime Trihydrate; FR 17027; FK 027; Cephixime; Suprax (Brand Name); CL 284,635; (Z)-Isomer of Cefixime
EINECS	Contact for details

Quality Control

Our Cefixime is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided, confirming compliance with specifications for assay, related substances, residual solvents, and microbiological quality. Our quality management system is designed to ensure consistent batch-to-batch reliability for pharmaceutical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0% (for trihydrate)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.2%
Microbiological Enumeration	Complies with EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.