Description

Proinsulin-Like Growth Factor Ii (117-156) is a synthetic peptide fragment corresponding to a specific region of the proinsulin-like growth factor II (IGF-II) molecule. This high-purity peptide is a critical research tool for studying the structure, function, and signaling pathways of IGF-II, a key regulator of cell growth, differentiation, and metabolism. It is essential for researchers and developers in pharmaceutical R&D, biochemical research, and diagnostic assay development who require precise and reliable bioactive peptides.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating IGF-II receptor binding, signal transduction mechanisms, and metabolic effects.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and development of therapeutics targeting growth disorders, diabetes, and cancer.
• Diagnostic Assay Production: Employed in the development and calibration of immunoassays (ELISA, RIA) for the quantitative measurement of IGF-II and related peptides in biological samples.
• Cell Culture & Physiology Studies: Applied in in vitro cell culture systems to study the effects of IGF-II on cell proliferation, differentiation, and survival.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies against the IGF-II protein.
• Structure-Activity Relationship (SAR) Studies: Utilized to map bioactive epitopes and understand the functional domains of the full-length IGF-II protein.

Basic Information

Product Name	Proinsulin-Like Growth Factor Ii (117-156)
CAS No.	108688-27-3
Molecular Formula	C185H294N52O57S2
Molecular Weight	~4250.8 g/mol
Synonyms	IGF-II (117-156); Insulin-like growth factor II fragment (117-156); Pro-IGF-II (117-156); Somatomedin-A (117-156); IGF-2 (117-156); Proinsulin-like growth factor II peptide fragment; CAS 108688-27-3
EINECS	Contact for details

Quality Control

Our Proinsulin-Like Growth Factor Ii (117-156) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A Certificate of Analysis (COA) detailing purity, peptide content, and analytical results is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.