Description

Nicotinamide Arabinoside Adenine Dinucleotide is a specialized, high-purity nucleotide coenzyme derivative. This compound is critical for research and development in advanced biochemical pathways, particularly those involving NAD+ metabolism and sirtuin activation. It serves as a key intermediate and reference standard for pharmaceutical, biotechnology, and life science research organizations focused on aging, metabolism, and cellular energy regulation.

Application

• Biochemical Research: Used as a critical substrate and reference standard in studies of NAD+-dependent enzymes, including sirtuins, PARPs, and CD38.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel therapeutics targeting age-related diseases and metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed in the formulation of high-sensitivity assay kits for measuring cellular NAD+ levels and enzymatic activity.
• Nutraceutical & Cosmeceutical R&D: Investigated for its potential role in precursor formulations aimed at supporting cellular health and longevity.
• Enzymology Studies: Essential for in vitro kinetic studies and characterization of dehydrogenases and other redox enzymes.
• Cell Culture & Metabolic Analysis: Used in specialized cell culture media and as a tool compound to modulate intracellular NAD+ pools in experimental models.

Basic Information

Product Name	Nicotinamide Arabinoside Adenine Dinucleotide
CAS No.	108646-17-9
Molecular Formula	C₂₁H₂₈N₇O₁₄P₂
Molecular Weight	664.44 g/mol
Synonyms	Arabinosyl Nicotinamide Adenine Dinucleotide; β-NAD (Arabinose); Ara-NAD; NAD (Arabinose); Nicotinamide Arabinoside Adenine Dinucleotide (oxidized form); 1-(5-O-Phosphono-β-D-arabinofuranosyl)-5-(5-O-Phosphono-β-D-ribofuranosyl)nicotinamide Adenine Dinucleotide; AraNMN-AD
EINECS	Contact for details

Quality Control

Our Nicotinamide Arabinoside Adenine Dinucleotide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, aliquots may be stored desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Biological Activity	Assayed in enzymatic system

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.