Description

2-Cyano-3-Hydroxy-n-(4'-Trifluoromethylphenyl)-Crotone Amide is a specialized organic compound featuring a cyano group, a hydroxyl group, and a trifluoromethylphenyl moiety, making it a valuable intermediate for advanced chemical synthesis. Its molecular structure is engineered to act as a key building block in the development of high-performance materials and active pharmaceutical ingredients (APIs). This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate unique fluorinated and cyano-functionalized motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, coatings, or liquid crystals with tailored optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds or fluorinated organic molecules.
• Dye and Pigment Intermediate: Utilized in the synthesis of advanced colorants and functional dyes due to its conjugated system and electron-withdrawing groups.

Basic Information

Item	Details
Product Name	2-Cyano-3-Hydroxy-n-(4'-Trifluoromethylphenyl)-Crotone Amide
CAS No.	108605-62-5
Molecular Formula	C₁₂H₉F₃N₂O₂
Molecular Weight	270.21 g/mol
Synonyms	2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]crotonamide; 3-Oxo-2-[(4-trifluoromethylphenyl)carbamoyl]butyronitrile; (2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide; 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonic acid amide; 2-Butenamide, 2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-, (2Z)-; Crotonamide, 2-cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-; KETO 007 (Potential R&D code)
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-3-Hydroxy-n-(4'-Trifluoromethylphenyl)-Crotone Amide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material meets high-purity requirements for research and development. A detailed Certificate of Analysis (COA) documenting all critical parameters is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.