Description

n-(Benzloxycarbonyl)-3-Amino-1 2- is a protected amino acid derivative, specifically a benzyloxycarbonyl (Cbz) protected diaminopropionic acid analog. This compound is a critical building block in organic synthesis, particularly in peptide chemistry, where it serves to protect the amine functionality during complex multi-step reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides, peptidomimetics, and other bioactive molecules. The product is supplied as a high-purity intermediate to ensure consistent results in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative to prevent unwanted side reactions.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed in the study of enzyme inhibitors, receptor ligands, and the structure-activity relationships of peptides.
• Prodrug Development: Utilized in designing prodrugs where the Cbz group provides a cleavable protective moiety.
• Material Science: Potential monomer for creating specialized polyamides or peptide-based polymers with unique properties.

Basic Information

Product Name	n-(Benzloxycarbonyl)-3-Amino-1 2-
CAS No.	108587-40-2
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	N-Cbz-2,3-diaminopropionic acid; (2R)-2-{[(Benzyloxy)carbonyl]amino}-3-aminopropanoic acid; Z-Dap-OH; Cbz-Dap-OH; Nα-Carbobenzoxy-2,3-diaminopropionic acid; N-[(Benzyloxy)carbonyl]-2,3-diaminopropanoic acid; 2,3-Diaminopropionic acid N-benzyloxycarbonyl derivative; 108587-40-2
EINECS	Contact for details

Quality Control

Our n-(Benzloxycarbonyl)-3-Amino-1 2- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.