Description

1-Palmitoyl-2-(12-((7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Amino)Dodecanoyl)Phosphatidylcholine is a high-purity, fluorescently labeled phospholipid derivative, specifically designed as a critical research tool. Its core value lies in the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore, which enables precise tracking and visualization of lipid dynamics in biological membranes. This compound is essential for researchers and developers in biophysics, cell biology, and pharmaceutical sciences who require reliable probes for studying membrane fusion, lipid trafficking, and model membrane systems.

Application

• Fluorescent Biomembrane Probe: Used to label and visualize artificial lipid bilayers (liposomes) and cellular membranes in real-time studies.
• Membrane Fusion & Trafficking Research: A key tool for investigating the mechanisms of vesicle fusion, endocytosis, and exocytosis.
• Lipid Raft and Domain Studies: Employed to study the organization and dynamics of specific lipid domains within membranes.
• Drug Delivery System Development: Acts as a traceable component in the formulation and efficacy testing of liposomal drug carriers.
• Biophysical Assays: Serves as a standard or reagent in fluorescence resonance energy transfer (FRET) and other spectroscopic techniques.
• Academic & Industrial R&D: Fundamental research reagent in universities, biotech, and pharmaceutical companies for basic and applied life science projects.

Basic Information

Product Name	1-Palmitoyl-2-(12-((7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Amino)Dodecanoyl)Phosphatidylcholine
CAS No.	108535-67-7
Molecular Formula	C₅₃H₉₃N₄O₁₂P
Molecular Weight	997.29 g/mol
Synonyms	NBD-PC; 1-Palmitoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-glycero-3-phosphocholine; NBD C12-HPC; 16:0-12:0 NBD PC; Fluorescent Phosphatidylcholine, NBD labeled; NBD Phosphatidylcholine; 1-Palmitoyl-2-(N-4-nitrobenzo-2-oxa-1,3-diazole)aminododecanoyl Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our NBD-labeled phospholipids are produced under stringent conditions to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic verification of the fluorophore. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting identity, purity, and fluorescence properties to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Solubility	Chloroform, Methanol, Ethanol
Fluorescence Properties	Excitation ~460 nm, Emission ~534 nm (in methanol)
Related Substances (HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.