Description

n-[(1S)-2-Hydroxy-1-Phenethyl)!Ethoxycarboxamide is a chiral, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for constructing complex molecules with precise stereochemistry. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it for developing active pharmaceutical ingredients (APIs), chiral catalysts, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity and environmental safety.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained amino acid analog for designing peptide-like molecules with enhanced metabolic stability and receptor selectivity.
• Chiral Catalyst & Ligand Preparation: Acts as a precursor for synthesizing sophisticated chiral ligands used in asymmetric catalysis for high-value chemical production.
• Academic & Industrial Research: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	n-[(1S)-2-Hydroxy-1-Phenethyl)!Ethoxycarboxamide
CAS No.	108493-65-8
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(S)-2-Hydroxy-2-phenylethyl carbamic acid ethyl ester; Ethyl N-[(1S)-2-hydroxy-1-phenylethyl]carbamate; L-Phenylglycinol carbamate ethyl ester; (S)-(-)-2-Phenyl-2-hydroxyethyl carbamate; Ethyl (S)-2-hydroxy-2-phenylethylcarbamate; NSC 339586; (1S)-2-Hydroxy-1-phenylethyl carbamic acid ethyl ester
EINECS	Contact for details

Quality Control

Our n-[(1S)-2-Hydroxy-1-Phenethyl)!Ethoxycarboxamide is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC/Chiral HPLC for purity and enantiomeric excess (ee) verification, alongside standard identification tests. Certificates of Analysis (COA) detailing all specifications are available for every batch and provided upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.