Description

(1R)-(+)-2,10-Camphorsultam CAS NO 108488-77-7 is a high-purity, enantiomerically pure chiral auxiliary and ligand widely used in asymmetric synthesis. Its value lies in its ability to induce high stereoselectivity in a variety of organic transformations, enabling the production of single-enantiomer compounds critical for advanced research and development. This product is essential for pharmaceutical chemists, agrochemical researchers, and fine chemical manufacturers involved in developing chiral active pharmaceutical ingredients (APIs), catalysts, and specialty intermediates.

Application

• Asymmetric Synthesis: As a versatile chiral auxiliary in aldol reactions, alkylations, and Diels-Alder reactions.
• Pharmaceutical Intermediates: For the stereoselective synthesis of single-enantiomer drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Preparation: Serving as a precursor for chiral catalysts and ligands used in metal-catalyzed asymmetric reactions.
• Agrochemical Research: In the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Process R&D: A key reagent for methodological development and scale-up studies in organic chemistry laboratories.
• Fine Chemical Production: For manufacturing high-value chiral flavors, fragrances, and advanced material precursors.

Basic Information

Product Name	(1R)-(+)-2,10-Camphorsultam
CAS No.	108488-77-7
Molecular Formula	C10H17NO3S
Molecular Weight	231.31 g/mol
Synonyms	(1R,4R)-7,7-Dimethyl-2-oxo-3-thia-1-azabicyclo[2.2.1]heptane 1,1-dioxide; (1R)-(+)-10-Camphorsulfonamide; (1R)-(+)-10,2-Camphorsultam; (1R,4R)-3-Thia-1-azabicyclo[2.2.1]heptane-2-one, 7,7-dimethyl-, 1,1-dioxide; (1R)-(+)-Camphorsultam; (R)-(+)-2,10-Camphorsultam; (+)-(1R,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonamide
EINECS	Contact for details

Quality Control

Our (1R)-(+)-2,10-Camphorsultam is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC for assay and chiral purity, NMR for structural confirmation, and optical rotation measurement. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Optical Rotation [α]20/D	+20.0° to +24.0° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.