Description

n-Desmethyldanofloxacin CAS NO 108461-04-7 is a key pharmaceutical intermediate and metabolite of the veterinary fluoroquinolone antibiotic, danofloxacin. This compound is of significant importance for research, development, and quality control within the animal health and pharmaceutical sectors. It is primarily utilized by manufacturers and analytical laboratories for the synthesis of reference standards, metabolite studies, and impurity profiling to ensure product safety and efficacy.

Application

• Pharmaceutical Reference Standard: Critical for the identification and quantification of danofloxacin and its related substances in quality control (QC) and quality assurance (QA) laboratories.
• Metabolite Research: Used in pharmacokinetic and metabolic studies to understand the absorption, distribution, metabolism, and excretion (ADME) profile of danofloxacin in animals.
• Impurity Profiling: Serves as a certified impurity standard to monitor and control the quality of active pharmaceutical ingredients (APIs) during manufacturing.
• Veterinary Drug Development: Employed in the research and development of new fluoroquinolone-based therapeutics and diagnostic methods.
• Analytical Method Development: Essential for developing and validating precise HPLC, LC-MS, or other chromatographic methods for residue analysis.
• Regulatory Compliance & Documentation: Supports regulatory submissions by providing characterized materials for stability studies and batch release testing.

Basic Information

Product Name	n-Desmethyldanofloxacin
CAS No.	108461-04-7
Molecular Formula	C19H20FN3O3
Molecular Weight	357.38 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Danofloxacin Impurity C; Danofloxacin Metabolite; 1-Ethyl-6-fluoro-1,4-dihydro-7-(4-ethyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid (obsolete); ADVANTIX Impurity C
EINECS	Contact for details

Quality Control

Our n-Desmethyldanofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.