Description

Pyr-Gln-Arg-Tyr-Gly-Asn-Gln-Trp-Ala-Val-Gly-D-Phe-Leu-Met-Nh2 CAS NO 108437-89-4 is a synthetic peptide sequence, also known as a fragment of the growth hormone-releasing hormone (GHRH). This compound is of significant interest for its role in stimulating the release of growth hormone, making it a valuable tool for biochemical research and pharmaceutical development. It is primarily utilized by research institutions and biotechnology companies focused on endocrinology, metabolic studies, and the development of novel therapeutic peptides.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating growth hormone secretion pathways and receptor binding.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of peptide-based therapeutics targeting growth disorders.
• Endocrinology Studies: Applied in in vitro and in vivo models to understand the regulation of the somatotropic axis.
• Diagnostic Development: Potential use in the formulation of assays and kits for measuring growth hormone-related biological activity.
• Academic Research: A critical reagent for universities and labs studying peptide synthesis, structure-activity relationships (SAR), and hormone biology.

Basic Information

Product Name	Pyr-Gln-Arg-Tyr-Gly-Asn-Gln-Trp-Ala-Val-Gly-D-Phe-Leu-Met-Nh2
CAS No.	108437-89-4
Molecular Formula	C78H118N24O19S
Molecular Weight	1695.96 g/mol
Synonyms	GHRH (1-14) amide, human; Growth Hormone-Releasing Hormone (1-14) amide; hGHRH(1-14)-NH2; Pyr-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (Note: This is a common core sequence; the provided full sequence is a specific analog); Tyr-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 fragment; GHRH analog; Somatoliberin fragment; Research Peptide 108437-89-4.
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of Pyr-Gln-Arg-Tyr-Gly-Asn-Gln-Trp-Ala-Val-Gly-D-Phe-Leu-Met-Nh2 undergoes rigorous purity verification using advanced chromatographic techniques. Certificates of Analysis (COA) detailing purity, identity, and content are provided with every shipment to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.