Description

Coenzyme A n-Valeryl Derivative (C5:0), Lithium Salt is a high-purity, chemically defined derivative of the essential metabolic cofactor Coenzyme A (CoA). This compound serves as a critical biochemical reagent and research standard for studying lipid metabolism, enzyme kinetics, and acyl-CoA-dependent pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in metabolic research, diagnostic assay development, and as a reference material.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays to study acyl-CoA synthetases, acyltransferases, and other enzymes involved in fatty acid metabolism.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the research and development of metabolic disorder therapeutics and enzyme-targeted drugs.
• Diagnostic Manufacturing: Employed in the formulation of in-vitro diagnostic (IVD) kits and calibrators for measuring specific metabolic markers in clinical samples.
• Metabolomics & Proteomics: Acts as a crucial standard for mass spectrometry (MS) and liquid chromatography (LC-MS/MS) based analysis to identify and quantify acyl-CoA species in complex biological samples.
• Enzyme Characterization: Essential for determining the kinetic parameters (Km, Vmax) and specificity profiles of enzymes that utilize valeryl-CoA as a substrate.
• Cell Culture & Media Supplementation: Used in specialized cell culture media to investigate the effects of specific acyl-CoA molecules on cellular metabolism and signaling pathways.

Basic Information

Item	Detail
Product Name	Coenzyme A n-Valeryl Derivative (C5:0), Lithium Salt
CAS No.	108392-07-0
Molecular Formula	C26H44N7O17P3Li
Molecular Weight	Approx. 843.55 g/mol (Lithium Salt)
Synonyms	Valeryl-Coenzyme A Lithium Salt; n-Valeryl-CoA Li Salt; Pentanoyl-Coenzyme A Lithium Salt; CoA-C5:0 Lithium Salt; CoASH(C5:0) Li Salt; S-Valerylcoenzyme A Lithium Salt; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-4-{[3-({2-[pentanoylsulfanyl]ethyl}amino)-3-oxopropyl]amino}-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate) Lithium Salt
EINECS	Contact for details

Quality Control

Our Coenzyme A n-Valeryl Derivative (C5:0), Lithium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications and results are available upon request to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.