Description

α-Nadp Sodium Salt is a high-purity biochemical reagent and a critical coenzyme essential for numerous dehydrogenase-catalyzed reactions. Its primary value lies in enabling precise enzymatic assays and research in redox metabolism, making it indispensable for scientific discovery and diagnostic development. This product is specifically needed by research institutions, pharmaceutical developers, and diagnostic kit manufacturers focused on metabolic pathways, enzyme kinetics, and high-throughput screening applications.

Application

• Enzymatic Research & Assay Development: Serves as an essential cofactor for NADP+-dependent dehydrogenases in kinetic studies and enzyme characterization.
• Diagnostic Reagent Manufacturing: A key component in clinical diagnostic kits for measuring substrates like glucose-6-phosphate, glutamate, and isocitrate.
• Pharmaceutical R&D: Used in drug discovery screens targeting metabolic enzymes and pathways, including those in cancer and metabolic disorder research.
• Cell Metabolism Studies: Facilitates the investigation of pentose phosphate pathway activity, antioxidant defense (glutathione reductase system), and lipid biosynthesis.
• Biochemical Production: Employed in enzymatic synthesis and biocatalysis processes requiring precise redox cofactor regeneration.
• Quality Control in Biotechnology: Used as a reference standard to calibrate and validate analytical methods in biopharmaceutical quality control labs.

Basic Information

Product Name	α-Nadp Sodium Salt
CAS No.	108392-03-6
Molecular Formula	C21H26N7Na3O17P3
Molecular Weight	833.36 g/mol
Synonyms	β-NADP Sodium Salt; Triphosphopyridine Nucleotide Sodium Salt; Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt; Coenzyme II Sodium Salt; TPN Sodium Salt; NADP+ Na3; Adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt, sodium salt (1:3)
EINECS	Contact for details

Quality Control

Our α-Nadp Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For extended use, store the working aliquot in a desiccator at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98%
Water Content (Karl Fischer)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Solubility	Clear, colorless solution in water
Biological Activity	Enzymatically functional in standard dehydrogenase assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.