Description

Syntide 2 CAS NO 108334-68-5 is a high-purity synthetic peptide substrate specifically designed for biochemical research and assay development. This compound is critical for studying and quantifying the activity of protein kinases, particularly Ca2+/calmodulin-dependent protein kinase II (CaMKII). It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors requiring precise and reliable kinase activity measurements.

Application

• Kinase Activity Assays: Primary substrate for in vitro assays measuring the activity of Ca2+/calmodulin-dependent protein kinase II (CaMKII).
• Drug Discovery & Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel kinase inhibitors or activators for therapeutic development.
• Biochemical Research: Serves as a specific tool for investigating kinase signaling pathways, enzyme kinetics, and phosphorylation mechanisms in cell-free systems.
• Diagnostic Kit Development: A key component in the formulation of ELISA and other diagnostic kits for research and clinical analysis of kinase-related diseases.
• Quality Control Testing: Employed in biopharmaceutical manufacturing for the potency testing and lot release of products targeting kinase pathways.

Basic Information

Product Name	Syntide 2
CAS No.	108334-68-5
Molecular Formula	C58H98N20O19
Molecular Weight	1371.5 g/mol
Synonyms	PLARTLSVAGLPGKK; CaMKII Substrate; Syntide-2; CaM Kinase II Substrate Peptide; CaMKII Substrate Peptide; Protein Kinase Substrate Syntide 2; Ca2+/Calmodulin-Dependent Protein Kinase II Substrate
EINECS	Contact for details

Quality Control

Our Syntide 2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to ensure compliance with research-grade specifications and support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be kept dry. For long-term storage, consider desiccant and under an inert atmosphere to prevent oxidation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.