Description

α-Nadph Sodium Salt CAS NO 108321-28-4 is the sodium salt form of the essential reduced coenzyme β-Nicotinamide Adenine Dinucleotide Phosphate (NADPH). This compound is critical as a primary biological reducing agent, facilitating numerous enzymatic reactions in metabolic pathways. It is indispensable for research and development in pharmaceutical discovery, clinical diagnostics, and life science research, particularly in studies involving redox biology, antioxidant defense systems, and biosynthetic processes.

Application

• Enzymatic Assay Reagent: Essential cofactor for dehydrogenase enzymes in diagnostic kits and research assays.
• Pharmaceutical Research: Used in drug discovery for studying metabolic pathways, cytochrome P450 systems, and oxidative stress responses.
• Biochemical Research: Critical for in vitro studies of cellular redox states, antioxidant mechanisms (e.g., glutathione reductase), and biosynthetic reactions like fatty acid and nucleotide synthesis.
• Diagnostic Manufacturing: Key component in the formulation of clinical diagnostic reagents for liver function, metabolic disorders, and genetic disease testing.
• Cell Culture & Metabolism Studies: Supports research into cellular energy metabolism and the pentose phosphate pathway.
• Industrial Biotechnology: Potential use in enzymatic synthesis and biocatalysis for the production of fine chemicals and chiral intermediates.

Basic Information

Product Name	α-Nadph Sodium Salt
CAS No.	108321-28-4
Molecular Formula	C21H26N7Na4O17P3 (or similar, based on hydration state)
Molecular Weight	~833.36 g/mol (anhydrous basis)
Synonyms	β-NADPH Sodium Salt; Reduced Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt; TPNH Sodium Salt; Coenzyme II Reduced Sodium Salt; NADPH-Na; Dihydrocodehydrogenase II Sodium Salt; 2'-NADPH Tetrasodium Salt; Triphosphopyridine Nucleotide Reduced Sodium Salt
EINECS	Contact for details

Quality Control

Our α-Nadph Sodium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Quality standards are aligned with requirements for research and in-vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). For short-term use, the unopened vial may be stored at 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95% (Typical ≥ 97%)
Absorbance Ratio (A340/A260)	≥ 2.0
Water Content (KF)	≤ 5.0%
Biological Activity	Enzymatically active (by coupled enzyme assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.