Description

Coenzyme A Tiglyl Derivative (C5:1), Lithium Salt is a high-purity biochemical intermediate, a specific derivative of the essential cofactor Coenzyme A. This compound is critical for research and development in metabolic pathways, particularly those involving fatty acid synthesis and degradation. It is primarily utilized by biopharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on enzymology and metabolic disease studies.

Application

• Biochemical Research: Used as a substrate or intermediate in the study of acyl-CoA synthetases, acyl-CoA dehydrogenases, and other enzymes involved in mitochondrial β-oxidation and branched-chain amino acid metabolism.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of enzymatic assay kits for clinical diagnostics, particularly for inborn errors of metabolism.
• Pharmaceutical Development: Employed in drug discovery programs targeting metabolic disorders, cancer metabolism, and other diseases where CoA-dependent pathways are dysregulated.
• Enzyme Characterization: Acts as a standard or reference compound for the kinetic analysis and inhibition profiling of metabolic enzymes.
• Metabolomics Studies: Used as an analytical standard in LC-MS or GC-MS workflows for the accurate identification and quantification of CoA derivatives in biological samples.

Basic Information

Product Name	Coenzyme A Tiglyl Derivative (C5:1), Lithium Salt
CAS No.	108320-99-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tiglyl-CoA, Lithium Salt; (E)-2-Methyl-2-butenoyl-CoA; Tiglyl-Coenzyme A; 2-Methylcrotonoyl-CoA; CoA Tiglyl Ester; Tiglyl-S-CoA; 3-Methylbut-2-enoyl-CoA; CoASH-Tig
EINECS	Contact for details

Quality Control

Our Coenzyme A Tiglyl Derivative (C5:1), Lithium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, identity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.