Description

Uridylyl(3'-5')Guanosine Ammonium is a high-purity dinucleoside monophosphate salt, a crucial building block in nucleic acid chemistry. Its primary value lies in its role as a key intermediate for the synthesis and research of oligonucleotides, RNA analogs, and other biologically active nucleotide derivatives. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require reliable, high-quality raw materials for advanced therapeutic and diagnostic development.

Application

• Oligonucleotide Synthesis: Serves as a critical phosphoramidite precursor or solid-phase synthesis intermediate for constructing specific RNA sequences.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving RNA polymerases, ligases, and nucleases.
• Antisense & siRNA Development: Acts as a fundamental component in the research and production of antisense oligonucleotides and small interfering RNA (siRNA) therapeutics.
• Diagnostic Probe Manufacturing: Incorporated into the production of labeled probes for techniques like FISH (Fluorescence In Situ Hybridization) and microarray analysis.
• Pharmaceutical Intermediates: Utilized in the development of nucleotide-based drugs targeting viral infections, genetic disorders, and cancers.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in nucleotide-related manufacturing.

Basic Information

Product Name	Uridylyl(3'-5')Guanosine Ammonium
CAS No.	108320-85-0
Molecular Formula	C19H27N9O13P · xNH3
Molecular Weight	Approx. 635.45 (Free acid) + NH3
Synonyms	3'-Uridylic-5'-guanosine Ammonium Salt; pUpG Ammonium Salt; Uridylyl(3'→5')guanosine ammonium; Uridine 3'-(guanosine 5'-pyrophosphate) ammonium salt; GU Ammonium Salt; Dinucleoside monophosphate (UpG) ammonium; 3'-UMP-5'-GMP ammonium; GU dinucleotide ammonium salt
EINECS	Contact for details

Quality Control

Our Uridylyl(3'-5')Guanosine Ammonium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment to maintain stability due to its hygroscopic nature. For long-term storage, keep under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Ammonium Content	As specified
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.