Description

n-(3-Nitro-2-Pyridinesulfenyl)-L-Glutamic Acid γ-T-Butyl Ester CAS NO 108312-25-0 is a specialized protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex molecules. It is primarily utilized in the pharmaceutical industry for the synthesis of peptides and other bioactive compounds, as well as in advanced chemical research for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic pathways and creating novel molecular entities.
• Agrochemical Synthesis: Serves as a precursor in the development of specialized active ingredients requiring protected glutamic acid moieties.
• Bioconjugation: Employed in the preparation of modified biomolecules for diagnostic and therapeutic applications.
• Material Science: Potential use in the synthesis of functionalized polymers and dendrimers with specific chemical handles.

Basic Information

Product Name	n-(3-Nitro-2-Pyridinesulfenyl)-L-Glutamic Acid γ-T-Butyl Ester
CAS No.	108312-25-0
Molecular Formula	C14H19N3O6S
Molecular Weight	357.38 g/mol
Synonyms	N-(3-Nitro-2-pyridinylthio)-L-glutamic acid 5-tert-butyl ester; L-Glutamic acid, N-(3-nitro-2-pyridinylthio)-, 5-(1,1-dimethylethyl) ester; N-(3-Nitro-2-pyridinesulfenyl)-L-glutamic acid γ-tert-butyl ester; Npys-Glu(OtBu)-OH; 3-Nitro-2-pyridinesulfenyl protected L-glutamic acid γ-t-butyl ester; (S)-2-((3-Nitro-2-pyridinyl)thio)pentanedioic acid 5-tert-butyl ester; Npys-L-Glu(OtBu)-OH; tert-Butyl (S)-2-((3-nitro-2-pyridyl)thio)pentanedioate
EINECS	Contact for details

Quality Control

Our production of n-(3-Nitro-2-Pyridinesulfenyl)-L-Glutamic Acid γ-T-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-20° to -25° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.