Description

Boc-Nva-Osu CAS NO 108233-37-0 is a high-purity, protected amino acid derivative widely used as a key building block in peptide synthesis. This compound is critical for researchers and manufacturers requiring precise and efficient coupling reactions to construct complex peptide chains. It is an essential reagent for pharmaceutical R&D, particularly in the development of novel therapeutic peptides, APIs, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled, sequential addition of norvaline residues under Boc (tert-butoxycarbonyl) protection strategy.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and peptide conjugates in solution, offering flexibility for specialized modifications.
• Pharmaceutical Intermediate: Serves as a key building block in the research and production of Active Pharmaceutical Ingredients (APIs) for peptide-based drugs.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of peptides to other molecules, such as dyes, polymers, or drug carriers, via its active ester group.
• Biochemical Research: Employed in academic and industrial laboratories to study protein structure-function relationships and to create custom peptide substrates or inhibitors.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive peptide leads.

Basic Information

Product Name	Boc-Nva-Osu
CAS No.	108233-37-0
Molecular Formula	C15H24N2O7
Molecular Weight	344.36 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-L-norvaline N-hydroxysuccinimide ester; Boc-L-norvaline-OSu; Boc-Norvaline-OSu; N-(tert-Butoxycarbonyl)-L-norvaline succinimidyl ester; N-Boc-L-norvaline N-succinimidyl ester; N-α-Boc-L-norvaline N-hydroxysuccinimide ester; (S)-2-((tert-Butoxycarbonyl)amino)pentanoic acid 2,5-dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Boc-Nva-Osu is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive applications like pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.