Description

α-Gliadin (43-49) CAS NO 107936-65-2 is a defined peptide fragment derived from the α-gliadin protein, a key component of wheat gluten. This specific sequence is of significant scientific and industrial interest for its role in celiac disease immunology and gluten protein research. It serves as a critical reference standard and active ingredient for researchers and developers in the life sciences sector. Primary applications include immunological studies, diagnostic assay development, and the formulation of specialized reagents.

Application

• Immunological Research: Used as a defined antigen to study T-cell epitopes and immune responses related to celiac disease and gluten sensitivity.
• Diagnostic Development: Serves as a key component in the development and calibration of ELISA kits and other immunoassays for detecting gluten-specific antibodies.
• Reference Standard: Acts as a high-purity analytical standard for quantifying gliadin content in food samples or research materials via HPLC or mass spectrometry.
• Biochemical Studies: Employed in structural biology and biochemistry research to investigate gluten protein functionality and interactions.
• Pharmaceutical R&D: Utilized in the research phase for developing novel therapies, such as tolerizing vaccines or enzymatic detoxification strategies for celiac disease.
• Food Safety Testing: Incorporated into method development for accurate detection and quantification of immunotoxic gluten peptides in "gluten-free" products.

Basic Information

Product Name	α-Gliadin (43-49)
CAS No.	107936-65-2
Molecular Formula	C35H55N9O12
Molecular Weight	793.87 g/mol
Synonyms	α-Gliadin Fragment 43-49; LQLQPFP; H-Lys-Gln-Leu-Gln-Pro-Phe-Pro-OH; Gliadin Peptide (43-49); Celiac Disease Immunogenic Peptide; Gluten Peptide α-2; α-Gliadin (43-49); Wheat Gliadin Peptide
EINECS	Contact for details

Quality Control

Every batch of α-Gliadin (43-49) is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.