Description

Rho1 Protein CAS NO 107898-34-0 is a high-purity, biologically active protein essential for research in cellular signaling and molecular biology. This product is critical for advancing studies in G-protein coupled receptor (GPCR) pathways, cytoskeletal dynamics, and intracellular transport mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on drug discovery and fundamental biological processes.

Application

• Biochemical Research: Used as a key reagent in the study of small GTPase signaling cascades and their role in cell physiology.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening (HTS) assays for identifying novel therapeutic compounds.
• Enzymology Studies: Employed in kinetic assays to investigate GTPase activity, nucleotide binding, and protein-protein interactions.
• Cellular Biology: Applied in cell-based assays to elucidate functions in vesicular trafficking, cytoskeleton organization, and cell division.
• Diagnostic Development: Potential use as a component in the development of diagnostic kits for research purposes.
• Protein-Protein Interaction Analysis: Utilized in techniques such as pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR).

Basic Information

Product Name	Rho1 Protein
CAS No.	107898-34-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RhoA Protein; Rho family GTPase 1; Ras homolog family member A; ARHA; RHO1; Transforming protein RhoA; Small GTP-binding protein RhoA; RHOA_HUMAN; p21-Rho1
EINECS	Contact for details

Quality Control

Our Rho1 Protein is produced under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, activity, and storage conditions is provided with every shipment to guarantee it meets the exacting standards required for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band at ~21 kDa
Purity (HPLC)	≥ 95%
Biological Activity (GTPase Assay)	Fully active
Endotoxin Level (LAL)	< 1.0 EU/μg
Protein Concentration	As per COA (typically 0.1 - 1.0 mg/mL)
Buffer Composition	Tris or HEPES buffer, with stabilizers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.