Description

(E)-3-Amino-3-(4-Chlorophenyl)-2-Propenenitrile is a versatile and high-value chemical intermediate characterized by its unique α,β-unsaturated nitrile structure with an amino group. This compound is crucial for the synthesis of complex heterocyclic systems and active pharmaceutical ingredients (APIs) due to its bifunctional reactivity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecular entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various nitrogen-containing heterocycles, such as pyridines, pyrimidines, and pyrroles, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including herbicides and fungicides, leveraging its chlorophenyl and nitrile functionalities.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in Michael addition reactions, cyclocondensations, and other C-C or C-N bond-forming transformations in academic and industrial R&D settings.
• Dye and Pigment Intermediate: Acts as a precursor for the manufacture of complex organic colorants and photographic chemicals.

Basic Information

Product Name	(E)-3-Amino-3-(4-Chlorophenyl)-2-Propenenitrile
CAS No.	107840-43-7
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	(E)-3-Amino-3-(4-chlorophenyl)acrylonitrile; 3-Amino-3-(4-chlorophenyl)-2-propenenitrile; 2-Propenenitrile, 3-amino-3-(4-chlorophenyl)-, (E)-; 4-Chlorobenzylidenecyanoacetamide precursor; (E)-3-Amino-3-(p-chlorophenyl)acrylonitrile; (E)-3-Amino-3-(4'-chlorophenyl)propenenitrile; 3-Amino-3-(4-chlorophenyl)acrylonitrile
EINECS	Contact for details

Quality Control

Our (E)-3-Amino-3-(4-Chlorophenyl)-2-Propenenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with customer and industry specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.