Description

1-Bromo-4-Ethoxy-2-Fluorobenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and electro-optical materials due to its electron-withdrawing characteristics.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating specialized chemical libraries in academic and industrial R&D settings.

Basic Information

Product Name	1-Bromo-4-Ethoxy-2-Fluorobenzene
CAS No.	107713-66-6
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	4-Bromo-1-ethoxy-2-fluorobenzene; 2-Fluoro-4-bromophenetole; 1-Ethoxy-4-bromo-2-fluorobenzene; 2-Fluoro-4-bromo-1-ethoxybenzene; 4-Bromo-2-fluoro-1-ethoxybenzene; 2-Fluoro-4-bromoanisole (common misnomer); p-Bromo-o-fluoroanisole (common misnomer)
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Ethoxy-2-Fluorobenzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.