Description

2-Methylsulfinyladenylcobamide is a specialized organosulfur derivative of adenosylcobalamin (Vitamin B12). This compound is significant for its role as a biochemical intermediate and research tool in the study of cobalamin-dependent enzymatic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel therapeutics and studying metabolic processes.

Application

• Biochemical Research: Used as a key intermediate or reference standard in the study of B12-dependent enzymes, particularly those involving methyl transfer reactions.
• Pharmaceutical Development: Serves as a precursor or building block in the synthesis of novel cobalamin-based drugs and targeted therapies.
• Enzymology Studies: Employed to investigate the mechanism of action of methionine synthase and other methylcobalamin-utilizing enzymes.
• Nutritional Science Research: Used in metabolic pathway analysis to understand the role of modified cobalamins in cellular function.
• Diagnostic Reagent Manufacturing: Can be incorporated into the development of advanced diagnostic kits and assays for metabolic disorders.
• Chemical Synthesis: Acts as a specialized reagent for introducing the adenosylcobamide structure into complex molecules.

Basic Information

Product Name	2-Methylsulfinyladenylcobamide
CAS No.	107688-04-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Methylsulfinyladenosylcobalamin; 2-Methylsulfinyl-AdoCbl; S-Methylsulfinyladenosylcobamide; Adenosylcobalamin sulfoxide derivative; Vitamin B12 sulfoxide analog; Coenzyme B12 sulfoxide; 5'-Deoxy-5'-adenosylcobamide sulfoxide
EINECS	Contact for details

Quality Control

Our 2-Methylsulfinyladenylcobamide is produced under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is verified using advanced techniques including HPLC and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation. For long-term storage, consider keeping the material desiccated at -20°C.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.