Description

Ribosomal Protein L19 is a highly specific protein component of the 60S ribosomal subunit, essential for protein biosynthesis. Its precise structure and function make it a critical reagent for advanced biochemical and molecular biology research. This protein is primarily utilized by research institutions and biopharmaceutical companies engaged in studies of ribosome assembly, function, and as a potential target for novel therapeutics.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating ribosome structure, assembly pathways, and translational mechanisms.
• Molecular Biology: Essential for in vitro reconstitution experiments of the large ribosomal subunit to study protein-RNA interactions.
• Drug Discovery & Target Validation: Serves as a potential target for developing novel antibiotics or chemotherapeutic agents that inhibit ribosomal function.
• Diagnostic Development: May be used in the development of assays to detect autoantibodies or study diseases linked to ribosomal protein dysregulation.
• Proteomics & Protein Interaction Studies: Employed in pull-down assays, mass spectrometry, and other techniques to map the interactome of the ribosomal complex.
• Educational & Reference Material: Supplied to academic laboratories for teaching advanced concepts in cell biology and genetics.

Basic Information

Product Name	Ribosomal Protein L19
CAS No.	107498-06-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RPL19; 60S ribosomal protein L19; L19; Ribosomal protein L19 (human); Large ribosomal subunit protein uL19; RPL19 protein
EINECS	Contact for details

Quality Control

Our Ribosomal Protein L19 is produced and handled under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a suite of analytical techniques including electrophoresis, chromatography, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity is provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band at appropriate molecular weight
Purity (HPLC)	≥ 95%
Protein Content (BCA/Bradford)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay (e.g., ribosome reconstitution)
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.