Description

Apolipoprotein C-II (Toronto) is a specific isoform of the Apolipoprotein C-II protein, a critical cofactor for lipoprotein lipase (LPL) enzyme activity. This compound is essential for research focused on lipid metabolism, hypertriglyceridemia, and cardiovascular disease mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers in the life sciences sector.

Application

• Biochemical Research: Used as a key reagent in studies of lipoprotein metabolism, LPL activation, and triglyceride clearance pathways.
• Diagnostic Development: Serves as a reference standard or antigen in immunoassays for measuring apolipoprotein levels in clinical samples.
• Therapeutic Target Investigation: Employed in drug discovery programs targeting dyslipidemia and related metabolic disorders.
• Cell Culture & In Vitro Studies: Used to modulate lipid processing in cellular models of atherosclerosis and metabolic syndrome.
• Protein-Protein Interaction Studies: Essential for characterizing binding interactions with LPL, lipoproteins, and other regulatory proteins.
• Quality Control Standard: Acts as a purity standard for the production and validation of related diagnostic kits and research tools.

Basic Information

Product Name	Apolipoprotein C-II (Toronto)
CAS No.	107497-50-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ApoC-II (Toronto); Apolipoprotein C2; Apo-CII; APOC2; Apolipoprotein C-II Isoform; Lipoprotein Lipase Activator; Hypertriglyceridemia-related Protein
EINECS	Contact for details

Quality Control

Our Apolipoprotein C-II (Toronto) is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment and functional activity verification, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content	≥ 90%
Biological Activity (LPL Activation)	Confirmed
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.