Description

(S)-2-Hydroxy-2-Cyclohexylacetonitrile is a high-value chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its core value proposition lies in its stereochemically defined structure, which is critical for imparting specific biological activity in advanced pharmaceutical compounds. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the development of enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance molecules, flavors, and advanced materials.
• Academic & R&D: Serves as a standard or starting material in methodological studies for new C-C bond formation and cyanohydrin chemistry.

Basic Information

Product Name	(S)-2-Hydroxy-2-Cyclohexylacetonitrile
CAS No.	107485-34-7
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Synonyms	(S)-2-Cyclohexyl-2-hydroxyacetonitrile; (S)-α-Hydroxycyclohexaneacetonitrile; (S)-Mandelonitrile, cyclohexyl-; (S)-Cyclohexylglycolonitrile; (S)-2-Hydroxy-2-cyclohexylethanenitrile; (1S)-2-Cyclohexyl-2-hydroxyacetonitrile; (S)-Cyclohexanemethanol, α-cyano-
EINECS	Contact for details

Quality Control

Our production of (S)-2-Hydroxy-2-Cyclohexylacetonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.