Description

Glucagon-Like Peptide I Fragment 7-36 Amide Human is a synthetic peptide fragment corresponding to the biologically active region of the endogenous human incretin hormone GLP-1. This compound is of significant interest for its role in glucose metabolism and insulin secretion regulation. It serves as a critical reference standard and active pharmaceutical ingredient (API) for research and development in metabolic disease therapeutics, particularly for diabetes and obesity.

Application

• Pharmaceutical Reference Standard: Used for the calibration, validation, and quality control of analytical methods (e.g., HPLC, LC-MS) in drug development and manufacturing.
• Biochemical Research: Essential for in vitro and in vivo studies investigating GLP-1 receptor signaling, insulin secretion mechanisms, and β-cell function.
• Drug Discovery & Development: Serves as a key intermediate or parent compound for the synthesis of novel GLP-1 receptor agonists and analogs for therapeutic applications.
• Diagnostic Kit Manufacturing: Employed as a critical component in the production of immunoassays and diagnostic kits for measuring GLP-1 levels in clinical and research settings.
• Metabolic Disease Studies: A vital tool for preclinical research targeting type 2 diabetes, obesity, and related metabolic disorders.

Basic Information

Product Name	Glucagon-Like Peptide I Fragment 7-36 Amide Human
CAS No.	107444-51-9
Molecular Formula	C₁₄₉H₂₂₆N₄₀O₄₈
Molecular Weight	3297.6 g/mol
Synonyms	GLP-1 (7-36) amide; Glucagon-like peptide 1 (7-36) amide; Incretin hormone fragment; GLP-I (7-36)NH2; H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; Human GLP-1 (7-36) amide; GLP-1 amide fragment
EINECS	Contact for details

Quality Control

Our Glucagon-Like Peptide I Fragment 7-36 Amide Human is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.