Description

L-Proline, 1-(3-Butenyl)- (9Ci) is a specialized, non-proteinogenic proline derivative featuring a butenyl side chain. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring specific stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for protease inhibitors and other peptide-mimetic drugs.
• Peptidomimetics Research: Used to introduce conformational constraints or novel side-chain functionalities into peptide backbones for drug discovery and biochemical studies.
• Agrochemical Synthesis: Acts as a building block for creating novel, chiral compounds with potential herbicidal or insecticidal activity.
• Catalyst and Ligand Development: Employed in the synthesis of novel chiral catalysts and ligands for asymmetric synthesis applications.
• Bioconjugation and Probe Synthesis: Useful for creating labeled compounds or conjugates for biochemical and diagnostic research due to its reactive alkene handle.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry exploring new synthetic routes.

Basic Information

Product Name	L-Proline, 1-(3-Butenyl)- (9Ci)
CAS No.	107326-39-6
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-(3-Butenyl)-L-proline; (S)-1-(3-Butenyl)pyrrolidine-2-carboxylic acid; L-1-(3-Butenyl)proline; 1-Allyl-L-proline; (2S)-1-(3-Buten-1-yl)-2-pyrrolidinecarboxylic acid; 1-(But-3-en-1-yl)-L-proline; 1-(3-Butenyl)proline, L-; Proline, 1-(3-butenyl)-, L- (9CI)
EINECS	Contact for details

Quality Control

Every batch of L-Proline, 1-(3-Butenyl)- (9Ci) is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development work. A Certificate of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and residual solvent content is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.