Description

Cathepsin G From Human Leukocytes is a serine protease enzyme derived from human white blood cells, playing a critical role in immune response and inflammatory processes. This high-purity enzyme is essential for researchers and developers in life sciences, enabling precise study of proteolytic pathways and immune system modulation. It is a vital reagent for pharmaceutical R&D, diagnostic assay development, and advanced biochemical research, where specificity and activity are paramount.

Application

• Biomedical Research: Used as a key tool enzyme to study neutrophil function, inflammation, and protease-activated receptor (PAR) signaling pathways.
• Pharmaceutical Development: Employed in screening for and characterization of novel serine protease inhibitors as potential therapeutic agents.
• Diagnostic Assay Manufacturing: Serves as a critical component in the development of enzymatic assays and diagnostic kits for immune and inflammatory disorders.
• Proteomics & Biochemistry: Utilized for protein digestion and peptide mapping in specialized research applications requiring specific cleavage sites.
• Cell Biology Studies: Applied in in vitro models to investigate extracellular matrix degradation and tissue remodeling processes.
• Quality Control & Standardization: Acts as a reference standard for activity assays in the production of related biopharmaceuticals.

Basic Information

Item	Details
Product Name	Cathepsin G From Human Leukocytes
CAS No.	107200-92-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cathepsin G; Cathepsin G, Human; Human Leukocyte Cathepsin G; CTSG; CG; Serine Protease Cathepsin G; Chymotrypsin-Like Protease; Neutrophil Cathepsin G
EINECS	Contact for details

Quality Control

Our Cathepsin G From Human Leukocytes is produced and tested under stringent quality management protocols to ensure high purity, specific activity, and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as activity (units/mg), purity level (by SDS-PAGE and HPLC), and absence of specified contaminant proteases. We adhere to relevant guidelines for biological sourcing and processing.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Keep container sealed under recommended conditions to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Activity)	Conforms (Specific activity provided on COA)
Purity (SDS-PAGE)	> 90%
Specific Activity	> 50 units/mg protein
Protein Content (Biuret)	Provided on COA
Solubility	Soluble in water or appropriate buffer
Endotoxin Level	< 1.0 EU/μg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.