Description

2-(12-(n-(4-Azido-2-Nitrophenyl))Aminododecanoyl)-1-Myristoylglycerol is a specialized, synthetic lipid derivative designed for advanced biochemical and biophysical research. This compound matters for its unique bifunctional structure, which incorporates a photoreactive azido group and a long-chain fatty acid, making it an essential tool for studying lipid-protein interactions and membrane dynamics. Researchers in pharmaceutical development, chemical biology, and advanced materials science need this high-purity reagent for photoaffinity labeling, probe synthesis, and model membrane system construction.

Application

• Photoaffinity Labeling Probe: Used to covalently capture and identify transient lipid-protein interactions in biological membranes upon UV light activation.
• Synthetic Lipid Synthesis: Serves as a key intermediate or functionalized building block for creating novel, tagged phospholipids and glycolipids.
• Membrane Biophysics Research: Incorporated into liposomes and lipid bilayers as a probe to study membrane fluidity, phase behavior, and domain formation.
• Drug Delivery System Development: Utilized in the design of functionalized lipid nanoparticles (LNPs) for targeted therapeutic delivery.
• Bioconjugation & Cross-linking: The reactive azido group enables specific conjugation to alkyne-modified biomolecules via click chemistry for diagnostic or imaging applications.
• Biochemical Tool Compound: Employed in enzymatic assays to study the activity of lipases, acyltransferases, and other lipid-metabolizing enzymes.

Basic Information

Product Name	2-(12-(n-(4-Azido-2-Nitrophenyl))Aminododecanoyl)-1-Myristoylglycerol
CAS No.	107141-10-6
Molecular Formula	C36H60N4O6
Molecular Weight	644.89 g/mol
Synonyms	1-Myristoyl-2-[12-[[(4-azido-2-nitrophenyl)amino]dodecanoyl]]-sn-glycerol; 2-(12-((4-Azido-2-nitrophenyl)amino)dodecanoyl)-1-tetradecanoylglycerol; N-[12-(1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoryloxy)dodecanoyl]-4-azido-2-nitroaniline (related phospholipid form); ANP-DD-MG; Photoactivatable Myristoylglycerol Derivative; Azido Nitrophenyl Labeled Lipid; Light-sensitive C14 Lipid Probe
EINECS	Contact for details

Quality Control

Every batch of 2-(12-(n-(4-Azido-2-Nitrophenyl))Aminododecanoyl)-1-Myristoylglycerol is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure high chemical purity and structural integrity, critical for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated freezer. This compound is strictly light-sensitive and hygroscopic. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation and thermal stress. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Yellow to orange viscous oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.