Description

3-Methyl-5,5,5-Trifluoropentanoic Acid is a versatile fluorinated carboxylic acid building block prized for its unique combination of a reactive acid group and a trifluoromethyl-terminated alkyl chain. This structure makes it a valuable intermediate for introducing lipophilicity and metabolic stability into target molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, influencing dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and hydrophobicity.
• Organic Synthesis Reagent: Acts as a versatile reagent for constructing complex organic molecules in medicinal and process chemistry research.
• Fluorinated Surfactant Precursor: Used in the development of specialty surfactants and surface coating agents with unique wetting and leveling characteristics.

Basic Information

Product Name	3-Methyl-5,5,5-Trifluoropentanoic Acid
CAS No.	107103-92-4
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	5,5,5-Trifluoro-3-methylpentanoic Acid; 3-Methyl-5,5,5-trifluorovaleric Acid; 5,5,5-Trifluorovaleric Acid, 3-methyl-; 3-Methyl-5,5,5-trifluoropentanoate; 107103-92-4; Valeric acid, 5,5,5-trifluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 3-Methyl-5,5,5-Trifluoropentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). As a strong acid/organic solvent, it should be kept away from incompatible materials such as strong bases and oxidizing agents. Ensure containers are properly labeled and sealed to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.