Description

5-Bromo-2',3'-Dideoxycytidine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile building block for the creation of novel antiviral and anticancer agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside-based therapeutics. The product is supplied with a focus on high purity and batch-to-batch consistency to support advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and antiretroviral drug candidates.
• Anticancer Research: Used in the development of nucleoside analogs designed to inhibit DNA synthesis in cancer cells.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies involving DNA polymerases and related enzymes.
• Prodrug Synthesis: A precursor for the development of prodrugs with enhanced bioavailability and targeted delivery.
• Organic Synthesis: Valuable intermediate for medicinal chemists to introduce bromo and dideoxy functionalities into complex molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Bromo-2',3'-Dideoxycytidine
CAS No.	107036-57-7
Molecular Formula	C9H12BrN3O3
Molecular Weight	290.12 g/mol
Synonyms	5-Bromo-ddC; 5-Bromo-2',3'-dideoxycytidine; 1-((2R,5S)-5-(Bromomethyl)tetrahydrofuran-2-yl)-5-amino-2,4(1H,3H)-pyrimidinedione; 5-Bromo-1-((2R,5S)-5-(bromomethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Br-ddC; NSC 614391
EINECS	Contact for details

Quality Control

Our 5-Bromo-2',3'-Dideoxycytidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.