Description

(S)-A-Hydroxybenzenepropanenitrile is a chiral, non-racemic organic compound featuring a benzylic hydroxy group adjacent to a nitrile functionality. This specific stereochemistry makes it a valuable chiral building block and synthetic intermediate for the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic and R&D: Employed in organic chemistry research for methodological studies in stereoselective synthesis and reaction development.

Basic Information

Product Name	(S)-A-Hydroxybenzenepropanenitrile
CAS No.	106863-50-7
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(S)-2-Hydroxy-3-phenylpropionitrile; (S)-3-Phenyl-2-hydroxypropionitrile; (S)-2-Hydroxy-3-phenylpropanenitrile; (S)-3-Phenyl-2-hydroxypropanenitrile; (S)-Phenyl lactonitrile; (S)-2-Cyano-1-phenylethanol; (S)-α-Hydroxybenzenepropanenitrile; (S)-β-Phenylglycidonitrile
EINECS	Contact for details

Quality Control

Our (S)-A-Hydroxybenzenepropanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.