Description

1-Bromo-4-(2,2,2-trifluoroethoxy)benzene is a high-value fluorinated aromatic building block, essential for introducing both bromine and trifluoroethoxy functional groups into complex molecular architectures. This compound is critical for applications demanding precise electronic and steric properties, offering a unique combination of reactivity and stability. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoroethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs), improving charge transport and device efficiency.
• Polymer Modification: Incorporated into specialty polymers and resins to impart unique solubility, thermal stability, and surface properties.
• Cross-Coupling Reactions: Acts as a versatile electrophile in palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) for constructing complex biaryl and conjugated systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	1-Bromo-4-(2,2,2-trifluoroethoxy)benzene
CAS No.	106854-77-7
Molecular Formula	C8H6BrF3O
Molecular Weight	255.03 g/mol
Synonyms	4-Bromo-1-(2,2,2-trifluoroethoxy)benzene; p-Bromo(2,2,2-trifluoroethoxy)benzene; Benzene, 1-bromo-4-(2,2,2-trifluoroethoxy)-; 4-(2,2,2-Trifluoroethoxy)bromobenzene; 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene; 4-Bromophenyl 2,2,2-trifluoroethyl ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.