Description

2-((9-Iodonon-2-Yn-1-Yl)Oxy)Tetrahydro-2H-Pyran is a specialized bifunctional organic intermediate featuring both a terminal alkyne and an alkyl iodide, protected by a tetrahydropyranyl (THP) ether group. This compound matters for its versatility as a key building block in advanced organic synthesis, enabling precise molecular construction through Sonogashira coupling and other cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating complex molecular architectures, including active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, particularly in constructing carbon frameworks via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its bifunctional nature allows for the introduction of specific alkyne and alkyl chains.
• Material Science Research: Serves as a monomer or precursor in the development of functional polymers, dendrimers, and advanced organic materials with tailored properties.
• Bioconjugation & Probe Development: Utilized in chemical biology for labeling biomolecules, where the alkyne handle enables "click chemistry" (CuAAC) for attaching fluorescent tags or other reporter groups.
• Liquid Crystal & OLED Precursor: Acts as a synthetic intermediate for creating rigid, conjugated structures used in electronic displays and organic light-emitting diodes (OLEDs).
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry laboratories and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2-((9-Iodonon-2-Yn-1-Yl)Oxy)Tetrahydro-2H-Pyran
CAS No.	106853-43-4
Molecular Formula	C14H23IO2
Molecular Weight	350.24 g/mol
Synonyms	9-Iodo-2-nonyn-1-ol Tetrahydropyranyl Ether; 2-(9-Iodonon-2-yn-1-yloxy)tetrahydro-2H-pyran; THP Ether of 9-Iodo-2-nonyn-1-ol; 1-(Tetrahydro-2H-pyran-2-yloxy)-9-iodonon-2-yne; Non-2-yn-1-ol, 9-iodo-, 1-(tetrahydro-2H-pyran-2-yl) ether; 2-[(9-Iodo-2-nonyn-1-yl)oxy]tetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 2-((9-Iodonon-2-Yn-1-Yl)Oxy)Tetrahydro-2H-Pyran is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for prolonged shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.