Description

2,3,4-Tri-o-Acetyl-D-Ribononitrile is a key protected ribose derivative, serving as a crucial chiral building block in organic synthesis. Its value lies in providing a versatile, reactive nitrile handle on a selectively acetylated sugar scaffold, enabling the construction of complex nucleoside analogs and other bioactive molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel therapeutics and specialty compounds.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of modified nucleosides, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used as a chiral synthon for creating novel pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances requiring sugar-based chirality.
• Biochemical Research: Employed in academic and industrial R&D for probing enzyme mechanisms and developing diagnostic probes.
• Nucleoside Chemistry: Fundamental starting material for the preparation of C-nucleosides and other carbohydrate-modified nucleic acid analogs.
• Glycoconjugate Synthesis: Used in the preparation of complex glycoconjugates for biological studies and material science.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-D-Ribononitrile
CAS No.	106820-14-8
Molecular Formula	C11H15NO7
Molecular Weight	273.24 g/mol
Synonyms	D-Ribononitrile, 2,3,4-triacetate; 2,3,4-Tri-O-acetyl-D-ribononitrile; 2,3,4-Tri-O-acetyl-D-ribo-pentodialdo-1,4-furanose nitrile; 1,4-Anhydro-2,3,5-tri-O-acetyl-D-ribitol-1-carbonitrile; Triacetyl D-ribononitrile; D-Ribose nitrile triacetate; 2,3,4-Triacetyl-D-ribononitrile
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-D-Ribononitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.