Description

tert-Butyl 3-Oxopyrazolidin-4-Ylcarbamate is a high-purity, specialized organic building block used in advanced pharmaceutical synthesis. This compound matters as a key intermediate for constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical and agrochemical industries for creating new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those containing pyrazolidinone or related heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a precursor for designing enzyme inhibitors or activity-based probes due to its reactive carbamate and ketone groups.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in kilo labs and pilot plants.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the custom manufacturing of more complex, proprietary compounds for client-specific applications.

Basic Information

Product Name	tert-Butyl 3-Oxopyrazolidin-4-Ylcarbamate
CAS No.	106693-44-1
Molecular Formula	C8H15N3O3
Molecular Weight	201.22 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3-pyrazolidinone; 4-Boc-amino-3-pyrazolidinone; tert-Butyl N-(3-oxo-2-pyrazolidinyl)carbamate; 1,2-Diazolidin-3-one, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-; BOC-4-amino-3-pyrazolidinone; 4-(Boc-amino)pyrazolidin-3-one; tert-Butyl (3-oxopyrazolidin-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxopyrazolidin-4-Ylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.