Description

Pyr-Glu-Asp-Ser-Gly-Oh CAS NO 106678-69-7 is a synthetic peptide sequence, also known as Pyroglutamyl-Aspartyl-Seryl-Glycine, with the CAS Registry Number 106678-69-7. This compound is a key building block in advanced peptide synthesis and biochemical research, valued for its defined structure and high purity. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Assay Development: Used as a substrate, inhibitor, or calibrant in enzymatic studies and the development of diagnostic assays.
• Proteomics & Peptide Mapping: Functions as a model peptide for mass spectrometry calibration and protein sequence analysis studies.
• Cosmeceutical Applications: Investigated for potential use in advanced skincare formulations targeting specific biological pathways.
• Academic & Institutional Research: Employed in university and government labs for fundamental studies in biochemistry, molecular biology, and medicinal chemistry.
• Custom Peptide Synthesis: Acts as a core fragment for the custom synthesis of longer, more complex peptide chains for specialized client projects.

Basic Information

Product Name	Pyr-Glu-Asp-Ser-Gly-Oh
CAS No.	106678-69-7
Molecular Formula	C17H24N5O11
Molecular Weight	474.40 g/mol
Synonyms	Pyroglutamyl-Aspartyl-Seryl-Glycine; pGlu-Asp-Ser-Gly-OH; 5-Oxo-L-prolyl-L-α-aspartyl-L-seryl-glycine; L-Pyroglutamyl-L-aspartyl-L-seryl-glycine; Pyr-Glu-Asp-Ser-Gly; pGlu-Asp-Ser-Gly; Glp-Asp-Ser-Gly-OH; CAS 106678-69-7
EINECS	Contact for details

Quality Control

Our Pyr-Glu-Asp-Ser-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for residual solvents and related substances. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.