Description

Amylin CAS NO 106602-62-4 is a synthetic 37-amino acid peptide hormone, also known as Islet Amyloid Polypeptide (IAPP), which plays a critical role in glucose metabolism. Its primary commercial value lies in its use as a high-purity reference standard and active pharmaceutical ingredient (API) in advanced diabetes and metabolic disorder research. This product is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutics for type 2 diabetes and obesity.

Application

• Pharmaceutical Reference Standard: Serves as a primary standard for the quantification and qualification of amylin and related analogs in analytical methods development and validation.
• Biomedical Research: Used in in vitro and in vivo studies to investigate its physiological role in satiety, gastric emptying, and glucagon secretion inhibition.
• Drug Discovery & Development: A critical starting material or intermediate in the synthesis and development of amylin mimetics and next-generation peptide therapeutics for metabolic diseases.
• Diagnostic Assay Development: Employed in the calibration and development of immunoassays (ELISA, RIA) for measuring amylin levels in clinical and preclinical samples.
• Mechanistic Studies: Utilized to study amyloid fibril formation and its implications in the pathology of type 2 diabetes and neurodegenerative diseases.

Basic Information

Product Name	Amylin
CAS No.	106602-62-4
Molecular Formula	C165H267N51O53S2
Molecular Weight	3903.4 g/mol
Synonyms	Islet Amyloid Polypeptide (IAPP); Human Amylin; Diabetes-Associated Peptide; Amylin (1-37) (human); DAP; hAmylin
EINECS	Contact for details

Quality Control

Our Amylin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and peptide content, Mass Spectrometry (MS) for identity confirmation, and tests for related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.