Description

Sertindole CAS NO 106516-24-9 is a high-purity atypical antipsychotic compound belonging to the phenylindole derivative class. It is a critical active pharmaceutical ingredient (API) valued for its specific dopaminergic and serotonergic receptor antagonism. This compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of neurological and psychiatric therapeutics, as well as for advanced pharmacological studies.

Application

• Primary Pharmaceutical Ingredient: Serves as the core Active Pharmaceutical Ingredient (API) in the formulation of antipsychotic medications.
• Neurological Research: Used as a reference standard and investigational compound in preclinical and clinical studies targeting schizophrenia and related psychotic disorders.
• Pharmacology Development: Employed in research to study the mechanisms of action of atypical antipsychotics on neurotransmitter systems.
• Analytical Standard: Utilized as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Formulation R&D: Integral to the research and development of new dosage forms, including tablets and controlled-release formulations.
• Regulatory Submissions: Supplied as a characterized substance for use in stability studies and documentation required for regulatory filings (e.g., with FDA, EMA).

Basic Information

Product Name	Sertindole
CAS No.	106516-24-9
Molecular Formula	C24H26ClFN4O
Molecular Weight	440.94 g/mol
Synonyms	1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone; Serdolect; Serlect; LU 23-174; 5-Chloro-1-(4-fluorophenyl)-3-[1-[2-(2-imidazolidinon-1-yl)ethyl]-4-piperidyl]-1H-indole
EINECS	Contact for details

Quality Control

Our Sertindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant internal specifications. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.