Description

(R)-(-)-2,2-Dimethylcyclopropane-1-Carboxamide CAS NO 106462-18-4 is a high-purity, single-enantiomer chiral building block featuring a constrained cyclopropane ring. This compound is of significant value in asymmetric synthesis and pharmaceutical research due to its stereochemical integrity and unique three-dimensional structure. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to introduce the chiral cyclopropane moiety into target molecules.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for use in enantioselective transformations.
• Material Science: Investigated as a monomer or additive for creating polymers with specific stereoregularity and physical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	(R)-(-)-2,2-Dimethylcyclopropane-1-Carboxamide
CAS No.	106462-18-4
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	(R)-2,2-Dimethylcyclopropanecarboxamide; (1R)-2,2-Dimethylcyclopropane-1-carboxamide; (R)-2,2-Dimethylcyclopropanecarboxylic acid amide; (R)-(-)-2,2-Dimethylcyclopropanecarboxamide; (R)-2,2-Dimethyl-1-cyclopropanecarboxamide; (R)-2,2-Dimethylcyclopropanecarboxylic acid amide; (R)-2,2-Dimethylcyclopropanecarboxamide; (R)-2,2-Dimethylcyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our (R)-(-)-2,2-Dimethylcyclopropane-1-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.